Steroid Profiling

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منابع مشابه

Steroid profiling--an update.

Extraction of steroids from urine with C18 solid-phase extraction cartridges results in an extract containing impurities. If, during the extraction of hydrolyzed urine, an amino (NH2) column is placed in series with the C18 column, then one obtains a sample that is sufficiently clean for gas-chromatographic analysis. Analytical recovery of dehydroepiandrosterone from urine is considerably decre...

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Endogenous steroid profiling in the athlete biological passport.

The Athlete Biological Passport (ABP) is an individual electronic document that collects data regarding a specific athlete that is useful in differentiating between natural physiologic variations of selected biomarkers and deviations caused by artificial manipulations. A subsidiary of the endocrine module of the ABP, that which here is called Athlete Steroidal Passport (ASP), collects data on m...

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Diagnostic Value of Urinary Steroid Profiling in the Evaluation of Adrenal Tumors

Radiological examination may unexpectedly reveal an adrenal mass. Current algorithms for differentiating between benign and malignant lesions mainly rely on size and densitometry on unenhanced CT, which have limited specificity. We examined the diagnostic value of urinary steroid profiling by gas chromatography/mass-spectrometry (GC/MS) in differentiating between benign and malignant adrenal tu...

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A case of virilzing adrenocortical carcinoma diagnosed by urine steroid profiling

Introduction Childhood adrenocortical carcinoma is rare and has poor prognosis. Histopathological examination often helps in differentiating between benign versus malignant adrenal tumors. However, the diagnostic accuracy of adrenal biopsies varies and could be affected by the sampling and the quality of the specimen. Urine steroid profiling (USP) has been used to differentiate between malignan...

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Steroid profiling reveals widespread local regulation of glucocorticoid levels during mouse development.

Glucocorticoids (GCs) are produced by the adrenal glands and circulate in the blood to coordinate organismal physiology. In addition, different tissues may independently regulate their local GC levels via local GC synthesis. Here, we find that in the mouse, endogenous GCs show tissue-specific developmental patterns, rather than mirroring GCs in the blood. Using solid-phase extraction, HPLC, and...

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ژورنال

عنوان ژورنال: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

سال: 1997

ISSN: 0004-5632,1758-1001

DOI: 10.1177/000456329703400106